Scientists working in the field of virology and veterinary bacteriology from Bern University in Switzerland have announced that they have managed to reconstruct coronavirus clones from synthetic DNA. Scientists who wanted to create a clone of the coronavirus first introduced DNA fragments of the coronavirus into yeast cells. They then combined the yeast cells with the coronavirus DNA fragments to create an accurate clone. From this composition, artificial yeast chromosomes were created, in which the genetic information of the coronavirus was stored. Scientists produced RNA without yeast cells using infectious RNA and then catalyst T7 RNA polymerase after forming the artificial chromosome. The resulting RNA was placed in an animal cell where the synthetic coronavirus can replicate, and eventually coronavirus clones were created. Professor Volker Thiel from Bern University Institute of Virology and Immunology, who took part in the creation of synthetic clones of the coronavirus, explained that they managed to reproduce coronavirus clones within a week using this method. Professor Jörg Jores from the University’s Veterinary Bacteriology Institute announced that they have optimized this system for the creation of synthetic clones of other viruses, to create synthetic clones of the coronavirus. Coronavirus clone will be used in vaccination studies The creation of synthetic clones of the coronavirus may bring to mind the conclusion that the coronavirus was created in the laboratory. However, this is absolutely not true. Synthetic clones of the coronavirus were not created from scratch; it is just an artificial reappearance of an existing virus, and these clones will be used to find coronavirus therapy and vaccine. Synthetic clones of viruses are used worldwide in vaccines and drug development studies against viruses. In this way, a sufficient number of viruses can be obtained and the process of developing vaccines and drugs can be made quite short.
